Scientists continue to develop effective ways to combat the signs of aging without surgery. Recent breakthroughs and technological advancements in non-invasive anti-aging procedures can make a more youthful appearance more accessible than ever. Here are a few treatment options you should know about.

1. Prescription-Grade Vitamin A

Concentrated formulas of skincare powerhouse vitamin A can do wonders for your skin, leaving over-the-counter varieties in the dust. Retinoids, a synthetic form of vitamin A, are one of the most effective treatments for anti-aging available. Tretinoin cream, a topical prescription, is one of the most popular choices, garnering fandom from individuals and celebrities alike. This retinoid increases collagen production, stops excess pigmentation, and even unblocks pores. Many report brighter, more vibrant skin along with smoother skin texture and even complexion.

Available in varying concentrations, users can start with a low dosage and work their way up, reducing potential irritation. With consistent use, increased collagen production speeds up skin renewal, resulting in a youthful, vibrant appearance. Tretinoin cream can be used at any age, meaning it can be effective as a preventative treatment, too. While retinoids shouldn’t be used while pregnant or nursing, they can be a lifelong treatment otherwise.

2. Microneedling With Platelet-Rich Plasma

Microneedling is a popular in-office treatment with increasing at-home usage, but adding platelet-rich plasma or PRP is revolutionary. PRP, the platelet-rich substance separated from a patient’s blood, is often injected into the body to incite healing. When used with microneedling, a process in which micro-injuries are created on the skin to encourage cell turnover, results follow.

By delivering the healing properties of PRP into new micro-injuries within seconds of their creation, collagen and elastin production increases. Generally, multiple treatment sessions are recommended to get the best results. After treatment, the skin may appear red, but many report tighter skin and increased radiance directly afterward. Plus, micro-needling with PRP can be effective on acne scars and hyperpigmentation, making it a multi-benefit treatment.

3. Silicone Patches

If you’ve ever used social media to search for skincare treatment, you’ve likely seen silicone patches. At-home versions of medical-grade wound care patches provide a great option for those opting for less invasive anti-aging. These patches are made of medical-grade silicone and cut into various face-friendly shapes.

Applied on clean, dry skin and left overnight, many report smoother skin upon waking and, with consistent use, fewer wrinkles long-term. As a non-chemical treatment, silicone patches are one of the most accessible treatments available. Patches can be applied to the face, neck, and chest, reducing tricky wrinkles that add to an aged appearance.

4. Alpha Hydroxy Acids

Alpha hydroxy acid or AHA has more nuance to it than a product label can convey. Acids are a critical component in an anti-aging routine with at-home and in-office variations for most skin types. Glycolic acid, derived from sugar cane, is the smallest AHA, making its absorption abilities superior. This acid exfoliates, reduces fine lines, prevents breakouts, and evens skin tone. You’ll find it in skincare products and as active ingredients in professional peels and microdermabrasion or microneedling treatments.

Those with sensitive skin or who are pregnant and nursing can maintain their anti-aging routine with the AHA lactic acid. Benefits include brighter, smoother skin, fewer fine lines and wrinkles, and fewer dark spots. Lactic acid, often derived from milk or sugar-rich foods, works by exfoliating the skin, revealing a bright, radiant complexion. Alternate use with retinol, as their combination may irritate, and always follow up with a moisturizer to lock in treatment.

5. Radiofrequency Laser

Administered in-office, radiofrequency laser treatment emits radiofrequency waves, which heat the dermal layer of the skin. This process stimulates collagen production, improving skin texture and lifting sagging skin. By heating the skin consistently for three or more minutes, proteins are released, putting the skin into repair mode.

It’s a relatively-painless procedure, and it can be administered in under an hour. It’s most effective earlier in the aging process or for those preferring more gradual improvements. This treatment can be used on all areas of the body, including the neck and chest. It’s also an option for treating sun damage, the reduction of which improves skin texture and color.

6. Red Light Therapy

If blue light is the enemy of your sleep schedule and skin condition, red light is your new best friend. A facialist favorite for years and used to help patients manage pain, red light therapy is increasingly used for anti-aging. New, accessibly-priced devices also make at-home use possible for more people, making this non-invasive treatment a must for your routine.

Administered through a flexible silicone mask or wand device, LED red lights emit low-frequency light to the skin. This process stimulates the cells that make collagen. Blood circulation increases, delivering more energy to tissues, which further support cell regeneration. The result is stronger, brighter, and more pliable skin — and a more youthful appearance.

Sample the Best Scientific Breakthroughs in Your Skincare Routine

Your grade school science class’s focus on the mitochondria finally gets top billing when plotting your science-backed anti-aging routine. Hacking cell growth, protein structure, and skin repair requires cutting-edge technology and ingredients. Explore these breakthroughs, assessing them to see what works best for you. When you do, you’ll be on your way to radiant, age-defying skin that’s supported by science.